Of course! You can update your payment method by logging into your usbank.com account or your U.S. Bank Mobile App. 
 
From your desktop: 

1. Log in to your usbank.com account.
2. Go to Bill payments at the top of the page.
3. Then, choose Pay bills & U.S. Banks accounts.
4. Choose which bill you'd like to update.
5. Then, find the account it's paid from.
6. Use the dropdown menu and choose the new account to pay from.
7. Choose Done and you're all set! 

 From your U.S. Bank Mobile App: 

1. Go to Pay bills at the bottom of the dashboard.
2. Choose Pay a bill.
3. Choose which bill you'd like to update.
4. Choose the balance displayed.
5. On the next screen, choose the Pay from field.
6. Update to the new account you'd like to pay from.
7. Tap Save and you're all set! 

 Remember that, if a transaction is currently pending, it won't be eligible to change.